Linking atypical depression and insulin resistance-related disorders via low-grade chronic inflammation: Integrating the phenotypic, molecular and neuroanatomical dimensions

Chronic Low-grade Inflammation after Exercise: Controversies

Low grade chronic inflammation in the RISC population: associations with insulin resistance and cardiometabolic risk profile

1 Institute for Research in Extramural Medicine, VU University Medical Center, Amsterdam, the Netherlands 2 Department of Clinical Sciences, Lund University, University Hospital, Malmö, Sweden 3 Metabolic Research Unit, St James’ Hospital, Trinity College, Dublin 8, Ireland 4 Unidad de Investigacion, Hospital Universitario La Paz, Madrid, Spain 5 Division of Therapeutical Teaching for Chronic D...

chronic low-grade inflammation after exercise: controversies

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Mechanisms Linking Inflammation to Insulin Resistance

Obesity is now widespread around the world. Obesity-associated chronic low-grade inflammation is responsible for the decrease of insulin sensitivity, which makes obesity a major risk factor for insulin resistance and related diseases such as type 2 diabetes mellitus and metabolic syndromes. The state of low-grade inflammation is caused by overnutrition which leads to lipid accumulation in adipo...

Linking Gut Microbiota and Inflammation to Obesity and Insulin Resistance.

Obesity and insulin resistance are the major predisposing factors to comorbidities, such as Type 2 diabetes, nonalcoholic fatty liver disease, cardiovascular and neurodegenerative diseases, and several types of cancer. The prevalence of obesity is still increasing worldwide and now affects a large number of individuals. Here, we review the role of the gut microbiota in the pathophysiology of in...